Organometallic chemistry in industry : a practical approach

Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world ex...

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Další autoři: Colacot, Thomas (Editor)
Seechurn, Carin C. C. Johansson (Editor)
Grubbs, Robert H. (Autor úvodu atd.)
Korporace: Wiley Online Library (online služba) (Distributor) 
Médium: E-kniha
Jazyk:angličtina
Vydáno: Weinheim : Wiley-VCH, 2020
Žánr/forma:sborníky
elektronické knihy
ISBN:978-3-527-81920-1
978-3-527-81919-5
978-3-527-81917-1
978-3-527-34517-5
9783527345175
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On-line přístup:Plný text
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245 0 0 |a Organometallic chemistry in industry :  |b a practical approach /  |c edited by Thomas J. Colacot, Carin C.C. Johansson Seechurn ; wit a foreword by Robert H. Grubbs 
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520 |a Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more. 
505 0 |a 1 Industrial Milestones in Organometallic Chemistry -- 2 Design, Development, and Execution of a Continuous-flow-Enabled API Manufacturing Route -- 3 Continuous Manufacturing as an Enabling Technology for Low-Temperature Organometallic Chemistry -- 4 Development of a Nickel-Catalyzed Enantioselective Mizoroki-Heck Coupling -- 5 Development of Iron-Catalyzed Kumada Cross-coupling for the Large-Scale Production of Aliskiren Intermediate -- 6 Development and Scale-Up of a Palladium-Catalyzed Intramolecular Direct Arylation in the Commercial Synthesis of Beclabuvir -- 7 Ruthenium-Catalyzed C-H Activated C-C/N/O Bond Formation Reactions for the Practical Synthesis of Heterocycles and Pharmaceutical Agents -- 8 Cross-couplings in Water - A Better Way to Assemble New Bonds -- 9 Aspects of Homogeneous Hydrogenation from Industrial Research -- 10 Latest Industrial Uses of Olefin Metathesis -- 11 Dehydrative Decarbonylation 
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