Drug metabolism concepts : a symposium co-sponsored by the Division of Medicinal Chemistry and the Division of Analytical Chemistry at the 172nd meeting of the American Chemical Society, San Francisco, Calif., August 31, 1976

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Další autoři: Jerina, Donald M. (Donald Michael), 1940-
Korporace: American Chemical Society. Division of Analytical Chemistry
American Chemical Society. Division of Medicinal Chemistry
American Chemical Society. Meeting
American Chemical Society (Distributor) 
Médium: E-kniha
Jazyk:angličtina
Vydáno: Washington, D.C. : American Chemical Society, 1977
Edice:ACS symposium series
Žánr/forma:elektronické knihy
ISBN:9780841203549
0841203547
0841203709
9780841203709
On-line přístup:Plný text
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Obálka
Obsah:
  • Cytochrome P-450 : its role in oxygen activation for drug metabolism / R.W. Estabrook and J. Werringloer
  • Synthetic models for the reaction stages of cytochrome P-450 / James P. Collman and Thomas N. Sorrell
  • Biochemical studies on drug metabolism : isolation of multiple forms of liver microsomal cytochrome P-450 / M.J. Coon, J.L. Vermilion, K.P. Vatsis, J.S. French, W.L. Dean, and D.A. Haugen
  • Resolution of multiple forms of rabbit liver cytochrome P-450 / Eric F. Johnson and Ursula Muller-Eberhard
  • Enantiomeric selectivity and perturbation of product ratios as methods for studying the multiplicity of microsomal enzymes / William F. Trager
  • Role of purified cytochrome P-448 and epoxide hydrase in the activation and detoxification of benzo[a]pyrene / W. Levin, A.W. Wood, A.Y.H. Lu, D. Ryan, S. West, A.H. Conney, D.R. Thakker, H. Yagi, and D.M. Jerina
  • In vitro reactions of the diastereomeric 9,10-epoxides of (+) and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo-[a]pyrene with polyguanylic acid and evidence for formation of an enantiomer of each diastereomeric 9,10-epoxide from benzo[a]pyrene in mouse skin / P.D. Moore, M. Koreeda, P.G. Wislocki, W. Levin, A.H. Conney, H. Yagi, and D.M. Jerina
  • Role of metabolic activation in chemical-induced tissue injury / Sidney D. Nelson, Michael R. Boyd, and Jerry R. Mitchell