Increasing the Therapeutic Ratio of Radiotherapy

Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal t...

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Bibliographic Details
Other Authors: Tofilon, Philip J (Editor)
Camphausen, Kevin (Editor)
Corporate Authors: SpringerLink (online služba)
Format: eBook
Published: Cham : Springer International Publishing , 2017
Series:Cancer Drug Discovery and Development
Genre/form:elektronické knihy
Online Access:Full-text
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Table of Contents:
  • Part 1. Molecular Targets
  • 1. Improving the therapeutic ratio of radiotherapy by targeting the DNA Damage Response
  • 2. Receptor Tyrosine Kinases as Targets for Enhancing Tumor Radiosensitivity
  • 3. Histone Deacetylase Inhibitors and Tumor Radiosensitization
  • 4. Radioprotection as a Method to Enhance the Therapeutic Ratio of Radiotherapy
  • Part 2. Microenvironment
  • 5. Application of Functional Molecular Imaging in Radiation Oncology
  • 6. Remodeling the Irradiated Tumor Microenvironment: The 5th R of Radiobiology?
  • 7. Combining Radiotherapy and Immunotherapy: Emerging Preclinical Observations of Lymphocyte Costimulatory and Inhibitory Receptor Modulation
  • Part 3. Clinical
  • 8. Stereotactic Body Radiation Therapy (SBRT) or Alternative Fractionation Schedules
  • 9. Novel Imaging for Treatment Planning or Tumor Response
  • 10. Increasing the Therapeutic Efficacy of Radiotherapy Using Nanoparticles
  • Index